Matlab ode45基本设置

Question

我试图用ode45模拟神经元的Morris-Lecar模型。

我在初始化ode45调用时遇到问题，文档无法帮助我。我知道我必须通过函数调用ode45，并从我的主脚本中调用该函数。

我对一般ODE的掌握有限，似乎无法理解初始化ODE45调用所需的语法。

此外，我被指示为变量'pulse'使用时间范围，但是在函数中没有时间范围的输入（这似乎是一个变量，不是固定的）主脚本并将其他函数发送到ode45函数。提供给ode45的函数也有时间输入，但是我再也不知道如何输入时间范围。说明非常清楚，主脚本中使用的函数不会占用任何时间变量。

如果您可以指出我在初始化过程中发生的任何明显错误，我们将非常感激。

电流（下同）版本的错误代码是如下：

Error using ODEequation (line 89) 
Not enough input arguments. 

Error in odearguments (line 88) 
f0 = feval(ode,t0,y0,args{:}); % ODE15I sets args{1} to yp0. 

Error in ode45 (line 114) 
[neq, tspan, ntspan, next, t0, tfinal, tdir, y0, f0, odeArgs, odeFcn, ... 

Error in ODEquestion (line 32) 
[t Vm]=ode45(@ODEequation,[-20 20],[-30, 0.1]',[],constants, stim_on, stim_off, amp); 

Error in YoonS_Lab3_EBME308_Fall2012 (line 355) 
[t Vm] = ODEquestion(20,100,30) 

我觉得这要追溯到我的不存在的，但需要时间投入。

问题涉及

Cm * dVm/dt = -Gm(Vm-Vrest) - Gca Minf (Vm - Eca) - Gk w(Vm - Ek) + pulse(t) 

dw/dt = (wInf - w)/Tau-w; 

wInf = (1+tanh(Vm/30))/2; 
mInf = (1+tanh(Vm+1))/2; 
Tau-w = 5/ (cosh(Vm/60)); 
Cm = membrane leakage capacticance; 
Gm = membrane leakage conductance; 
Vm = membrane voltage; 
Vrest = membrane voltage @ neuron resting 
Gca = max Ca conductance through membrane 
Gk = max K conductance through membrane; 
mInf refers = P (Ca ion channel open) 
wInf refers = P (K ion channel open) 
Tau-w = rate which K channels respond to change in membrane voltage 
Eca = reversal potential of Ca 
Ek = reversal potential of K 
pulse(t) = stimulus applied to neuron 
pulse(t) = A (stim-on <= t <= stim-off) or 0 (else); 

的变量。

我创建了一个函数发送到ode45，如下所示。

function dy = ODEequation(t, Vm, w, constants, stim_on, stim_off, amp) 

wInf = (1 + tan(Vm/30))/2 
mInf = (1 + tan((Vm + 1)/ 15))/2 
tauW = 5/ (cosh(Vm/60)) 

pulse = amp * ((stim_on < t) - (t >= stim_off)); 

dy(1) = y(1) * ((-constants(2) - constants(4) * constants(9) - constants(5) * y(2)) + (constants(2) * constants(3) + constants(6) * constants(4) * constants(9) + constants(5) * y(2) * constants(7) + constants(11)))/constants(1) ; 
dy(2) = = (constants(8) - y(2))/constants(10) 
dy = dy' 

并且通过该函数是如下

function [t Vm] = ODEquestion(stim_on, stim_off, amp) 

%i) 
Cm = 1; 
Gm = 0.5; 
Vrest = -50; 
Gca = 1.1; 
Gk = 2; 
Eca = 100; 
Ek = -70; 

%ii) 
Vm(1) = -30; 
w(1) = 0.1; 

%iii) 
wInf = (1 + tan(Vm/30))/2 
mInf = (1 + tan((Vm + 1)/ 15))/2 
tauW = 5/ (cosh(Vm/60)) 


IC1 = Vm(1) % = -30 
IC2 = w(1) % = 0.1 

pulse = amp %* ((stim_on < t) - (t >= stim_off)); 

constants = [Cm , Gm, Vrest, Gca, Gk, Eca, Ek, wInf, mInf, tauW, pulse]; 

[t Vm]=ode45(@ODEequation,[-20 20],[-30, 0.1]',[],constants, stim_on, stim_off, amp); 

Answer 1

从help ode45：

ODE45解决非刚性微分方程，介质顺序方法。

[TOUT,YOUT] = ODE45(ODEFUN,TSPAN,Y0) with TSPAN = [T0 TFINAL] integrates 
the system of differential equations y' = f(t,y) from time T0 to TFINAL 
with initial conditions Y0. ODEFUN is a function handle. For a scalar T 
and a vector Y, ODEFUN(T,Y) must return a column vector corresponding 
to f(t,y). 

因此函数ODEFUN预计只有两个输入（t和y），而你的函数需要7个输入。

可以通过以下对this site，或this question发现指令解决这个问题：

wrapper = @(t,Vm) ODEequation(t, Vm, w, constants, stim_on, stim_off, amp); 
[t Vm]=ode45(wrapper, [-20 20],[-30, 0.1]',[],constants, stim_on, stim_off, amp); 

例如，通过创建穿过所有的常数而转发由ode45插入变量小包装函数。