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我有一个GI(genbank标识符)号码列表。我如何获得每个GI号码的序列描述(如'mus musculus hypothetical protein X'),以便我可以将它存储在一个变量中并将其写入文件? 感谢您的帮助!如何通过biopython从gi编号获取序列描述?
我有一个GI(genbank标识符)号码列表。我如何获得每个GI号码的序列描述(如'mus musculus hypothetical protein X'),以便我可以将它存储在一个变量中并将其写入文件? 感谢您的帮助!如何通过biopython从gi编号获取序列描述?
因此,如果任何人有这样的疑问,这里是解决方案:
handle=Entrez.esummary(db="nucleotide, protein, ...", id="gi or NCBI_ref number")
record=Entrez.read(handle)
handle.close()
description=record[0]["Title"]
print description
这将打印对应的标识序列描述。
这是我写的一个脚本,用于为文件中的每个genbank标识符提取整个GenBank文件。应该很容易为您的应用程序进行更改。
#This program will open a file containing NCBI sequence indentifiers, find the associated
#information and write the data to *.gb
import os
import sys
from Bio import Entrez
Entrez.email = "yo[email protected]" #Always tell NCBI who you are
try: #checks to make sure input file is in the folder
name = raw_input("\nEnter file name with sequence identifications only: ")
handle = open(name, 'r')
except:
print "File does not exist in folder! Check file name and extension."
quit()
outfile = os.path.splitext(name)[0]+"_GB_Full.gb"
totalhand = open(outfile, 'w')
for line in handle:
line = line.rstrip() #strips \n from file
print line
fetch_handle = Entrez.efetch(db="nucleotide", rettype="gb", retmode="text", id=line)
data = fetch_handle.read()
fetch_handle.close()
totalhand.write(data)
检查了这一点,让你开始:http://biopython.org/DIST/docs/api/Bio.Entrez-pysrc.html – heathobrien